Sentence examples for binding sequences such as from inspiring English sources

The existence of unusual GlnR binding sequences, such as that found upstream of nasA, implies that there may be other, as yet undiscovered, GlnR target genes.

The SNP rs3021529 is located within several transcription factor binding sequences, such as for the enhancer and for the transcriptional repressor that repress neuronal genes in non-neuronal tissues.

Studies by Carroll and colleagues have shown that ERs only sometimes regulate genes using EREs from proximal promoter regions and generally use distal enhancers and other binding sequences, such as Forkhead binding sites [ 31].

In Table 1, 19 of these 27 HS-binding CPPs generally possess conventional heparin binding sequences such as XBBXB and XBBBXXBX where B is a basic amino acid and X represents a random amino acid, and they can also be divided into cationic and amphipathic groups.

The two E2F sites identified do not conform to classical E2F-binding consensus sequences, such as those found in the DHFR promoter.

Twelve different IgE-binding protein sequences, such as thioredoxin (cross-reactive allergens), a predicted high mobility protein, a predicted leucine-rich repeat protein, a beta-purothionin precursor and the serine carboxypeptidase II were also identified using Western blotting against patients' sera (Sampedro and Cosgrove 2005; Weichel et al. 2006).

Biochemical studies have demonstrated that Twist1 and Hand1/2 formed hetero-dimers or homo-dimer with E12, E47 and between themselves to activate or suppress transcription of downstream target genes through binding E-box sequences such as the degenerate Thing1-box, CGTCTG, in the cis-regulatory elements of target genes [1], [6], [9], [10], [11].

Initial results showed that DB2277 has excellent sequence selectivity and strong binding affinity with sequences such as AAA GTTT.

Many known ncRNAs exhibit their functionality through binding of RNA target sequences, such as microRNAs bind mRNAs, snoRNAs bind ribosomal and small nuclear RNAs, and certain lncRNAs may bind microRNAs [ 53] to regulate their activity or guide RNA editing.

PRH may also repress transcription by binding to AT-rich sequences such as those found in TATA boxes and competing with TBP for binding to these sites.

Sp1, the prototype of a family of zinc finger (Cys2/Hys2) DNA binding transcription factors, binds to GC-rich sequences such as GC box (40).