Sentence examples for binding sequences for the from inspiring English sources

One region within block 2 that was particularly sensitive to mutation contains consensus binding sequences for the factors HNF1 and INSM1, which have been previously implicated in development and function of pancreatic islets [33].

These results indicate that these additional DNA fragments provided binding sequences for the degenerate or vector-specific primers (Additional file 3: Figure S2B, C).

Sequencing a total of 512 single product colony-PCR reactions, we successfully obtained 235 potential binding sequences for the mouse library, and 197 for the zebrafish library.

Briefly, a PWM compiles information content (log odd values) for each nucleotide position using existing information on known binding sequences for the protein of interest.

Among the common promoter elements found, 4 were similar to known binding sequences for the S. cerevisiae transcription factors Rap1p, Adr1p and Hcm1p.

Input sequences are screened for consensus binding sequences for the SR proteins SF2/ASF, SC35, SRp40 and SRp55, developed using the SELEX (systematic evolution of ligands by exponential enrichment) procedure [ 11, 21, 22].

The consensus DNA binding sequences for these bHLH proteins form the typical E boxes (CANNTG).

The Oligo-histidine tag should serve as a high affinity binding sequence for the purification of any fusion protein via metal chelating adsorbents.

These motifs are not exact strings: while most binding sites for a given factor resemble a "consensus string" (for example, ACGCGT, the most common binding sequence for the MBP1 protein in budding yeast), mismatches and variations often occur.

Kinase activity was assayed using a synthetic NH2-terminal biotin linked peptide substrate containing the consensus binding sequence for the ABL kinase (biotin-EAIYAAPFAKKK-amide; New England Peptide, Gardner, MA, USA) [42], [43].

They must be clinically relevant and fulfil the following requirements: to have a hormone response element sequence in its promoter region; the hormone must effectively impact on its expression (not only having a binding sequence for the nuclear receptor) and its expression should be influenced by the interaction with other transcription factors.