Sentence examples for binding sequences can be from inspiring English sources
In this investigation chromatin immunoprecipitation (ChIP) experiments and bioinformatic methods were used to analyze if these binding sequences can be verified on chromatin of living cells as well.
In practice, multiple rounds of selection and expansion are required before unique tightly binding sequences can be identified.
Identification of transcription-factor binding motifs (DNA sequences) can be formulated as a combinatorial problem, where an efficient algorithm is indispensable to predict the role of multiple binding motifs.
Although it is difficult to determine the precise binding site, the footprint sequences can be used as an estimate of the potential palindromicity of the experimentally characterised binding regions.
To enhance the mAb antigen specificity and binding affinity, the amino acid sequences can be modified at the mAb antigen binding site [ 38, 39].
All the members of this superfamily have conserved nucleotide, phosphate and magnesium binding sequences but the Rab sequences can be distinguish by their C-terminal prenylation site and five Rab-specific regions (RabF) [ 53].
Transcription factor binding sites and other cis-regulatory sequences can be particularly important in the evolutionary adaptation of humans.
Consequently binding of Drosha to nascent miRNA sequences can be detected using chromatin immunoprecipitation (ChIP) analysis (Morlando et al., 2008).
Based on the predicted parameters, positive gold-standard sequences can be scanned to find all potential binding sites with binding affinities higher than the cutoff score.
Whereas the CHCC zinc-binding motif is highly conserved, the remaining sequences can be rather divergent even within the yeast group.
