Sentence examples for binding sequence which is from inspiring English sources

Cortactin contains a consensus c-Src SH2 binding sequence which is adjacent to Tyr421 that was shown to bind the SH2 domain of c-Src.

The extreme C terminus of PTEN contains a PDZ-domain binding sequence, which is required for the interaction of the phosphatase with several PDZ-domain-containing proteins.

These motifs include the canonical 'core origin,' defined as the minimal DNA requirement for the initiation of replication, binding the terminal protein-DNA polymerase complex [38], and several host transcription factor binding sequences which are required for efficient adenovirus replication [39], [40].

In fact, FoxO1 bound directly to the FRE site within the FoxO1 promoter, whereas phosphorylation of FoxO1 by FSH dissociated FoxO1 from its DNA-binding sequence, which was correlated with the downregulation of FoxO1 expression.

4E-BPs and eIF4G compete for binding to the eIF4E dorsal surface via a shared canonical 4E-binding motif, but also contain auxiliary eIF4E-binding sequences, which were assumed to contact non-overlapping eIF4E surfaces.

The OGG1 promoter contains ARE sequences, that is, Nrf2-binding sequences, which are activated under antioxidant or electrophilic conditions in a normal redox state [ 14, 15].

Therefore, we selected 115 AdpA-binding sequences, which were located within 30 bp from the centre of each DNA fragment (130 200 bp), and compared in vitro AdpA-binding strength to in vivo AdpA-binding strength deduced from ChIP/ChAP-seq signal intensities (average values) (Fig.  5).

Combining editome sequencing from ADAR1 knockdown cells and protein immunoprecipitation, Wang et al. strengthened this hypothesis by identifying an enrichment of HuR-binding sequences, which are implicated in transcript turnover and processing, around editing sites and on ADAR-bound transcripts, respectively [ 43].

This method shows that exact DNA-binding sequences, which were protected from in vivo DNase I digestion, were resolved at a comparable resolution to that achieved by in vitro DNase I footprinting, and this was simply attained without the necessity of prediction by peak-calling programs.

The next highest τD value is exhibited by the probe binding the 0302 sequence, which is the only one displaying a base composition identical to that of the 0201 allele at codon 57.

The basic algorithm described above assumes that there is one and only one binding site on each sequence, which is certainly not always true.