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Therefore, taken together, our data suggest that one possible receptor for β43 63 could be a non-RGD binding sequence on the αv β3 integrin.
To map the vimentin binding sequence on the C-terminus of SERT, we utilized the truncated form of transporters, Δ26, Δ20, Δ14, and Δ6 [15].
In this regard, Guo and co-workers demonstrated a decreased binding of KLF6 to its DNA binding sequence on the Tissue Factor Pathway Inhibitor-2 (TFPI-2) gene due to CpG hypermethylation in highly invasive breast cancer cell lines, suggesting a tumor suppressor function of KLF6 [30].
Many enzymes that catalyze post-translational modifications recognize a specific binding sequence on the substrate.
This evidence is strengthened by the presence of the GLI1 consensus binding sequence on the Cyclin D2 promoter [ 13].
This fact makes it difficult to detect all the binding sites corresponding to a global regulator without a specific definition of their binding sequence on the DNA.
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Transcription factor (TF) binding sites are then predicted by detecting statistically significant TF binding sequences on the genome using a position weight matrix.
It was made possible by our identification of an integrin binding sequence on uPAR [5] and the recently published crystal structure of uPAR [6].
Moreover the binding sequence on Msp2 remains undefined.
48 It is therefore reasonable to expect some degree of coiling of molecular chains on PEG-based SAMs, which ultimately decreases the effective number of spacer molecules that are able to present the cRGD binding sequence on a fully extended connector ligand.
Enzymatic DNA footprints suggest displacement of the XerC recombinases from their specific DNA-binding sequences on the pseudo-HJ.
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