Sentence examples for binding sequence of the from inspiring English sources

Binding of a TF to a gene regulatory region requires a match between the binding sequence of the TF and the operator region of that particular gene.

A reporter construct carrying a point mutation within the FoxO binding sequence of the CTDSP2 promoter region had significantly reduced luciferase activity in all conditions (Fig. 3e).

Bell and colleagues reported that the binding sequence of the transcription factor CTCF is necessary and sufficient for enhancer insulation activity of HS4 of the chicken β-globin locus [19].

However, the conservation or divergence of the binding sequence of the family members in each clade needs to be further investigated.

These three base-pairs essentially determine the binding sequence of the TF, because these proteins usually form homo-dimers in which each monomer recognizes the same sequence [ 13].

Plasmid pJM7 contains mutations−57GA and −56TA, forming an A5 tract extending from positions −57 to −53, matching the preferred binding sequence of the αCTD.

At the resolution achieved chromosome-wide, we did not find a statistically significant correlation between the predicted binding sequences of the two alleles and recombination rates (Table S5).

The empirical binding sequences of the TFs are reported [3], [9] in an extended alphabet (e.g. "rACGCGt" for the transcription factor MBP1) specifying the base preferences or the binding affinities as a set of letters with variable case.

We examined the 1,532 AR-binding sites identified by ChIP-chip for the presence of ARE-like sequences, to determine the preferred binding sequences of the AR.

This change in linker symmetry and directionality is expected to have a corresponding influence on the directionality of the preferred DNA binding sequences of the different molecules.

These observations reveal that the binding sequences of the HAP complex and its target genes have been conserved during the evolution of aerobic fermentation.