Sentence examples for binding sequence for the from inspiring English sources
The Oligo-histidine tag should serve as a high affinity binding sequence for the purification of any fusion protein via metal chelating adsorbents.
These motifs are not exact strings: while most binding sites for a given factor resemble a "consensus string" (for example, ACGCGT, the most common binding sequence for the MBP1 protein in budding yeast), mismatches and variations often occur.
Kinase activity was assayed using a synthetic NH2-terminal biotin linked peptide substrate containing the consensus binding sequence for the ABL kinase (biotin-EAIYAAPFAKKK-amide; New England Peptide, Gardner, MA, USA) [42], [43].
They must be clinically relevant and fulfil the following requirements: to have a hormone response element sequence in its promoter region; the hormone must effectively impact on its expression (not only having a binding sequence for the nuclear receptor) and its expression should be influenced by the interaction with other transcription factors.
Interestingly, the miR-106b~25 genomic locus contains a consensus binding sequence for the FoxO transcription factors.
A significant match was identified to the consensus binding sequence for the cyclic-AMP receptor protein (CRP) of E. coli.
One region within block 2 that was particularly sensitive to mutation contains consensus binding sequences for the factors HNF1 and INSM1, which have been previously implicated in development and function of pancreatic islets [33].
Sequencing a total of 512 single product colony-PCR reactions, we successfully obtained 235 potential binding sequences for the mouse library, and 197 for the zebrafish library.
Briefly, a PWM compiles information content (log odd values) for each nucleotide position using existing information on known binding sequences for the protein of interest.
Among the common promoter elements found, 4 were similar to known binding sequences for the S. cerevisiae transcription factors Rap1p, Adr1p and Hcm1p.
These results indicate that these additional DNA fragments provided binding sequences for the degenerate or vector-specific primers (Additional file 3: Figure S2B, C).
