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However, the order of the binding sequence and binding affinities to the individual receptor subunits differ markedly between the two cytokines.
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Mithramycin has affinity for the GGGCGG binding sequence, and effectively blocks the binding of Sp1 [24].
We obtained two unique SEB binding sequences, one ricin binding sequence and two BoNT/A complex toxoid binding sequences.
GAL4-DBD is capable of binding DNA containing its specific binding sequence, and TfRscFv binding TfR on tumor cells is able to uptake by tumor cells through cell membranes to deliver DNA.
We report for each domain ligand protein interaction pair (i) the sequence ID, (ii) the ligand binding position, (iii) the ligand binding sequence and (iv) the ligand binding domains.
By searching for promoters containing a consensus GlnR-binding sequence and verifying GlnR binding activity in vitro, they identified 10 new GlnR targets.
Similar to the human MMPs, the predicted primary structures of plant MMPs contain a signal peptide, a prodomain with the cysteine-switch motif and a catalytic domain containing the active zinc-binding sequence and structural zinc- and calcium-binding site followed by the conserved Met-turn [ 11– 13].
M PEAK relies on the fact that multiple probes will bind the same chromatin fragment if the probes are designed to be close together along the genomic sequence, with maximal binding seen where the probe sequence and the binding element overlap.
NF-κB dimers bind to different κB sequences with different binding affinities and binding modes.
mSr is defined as, where Np is the number of transcription factors with at least one correctly predicted binding site in the binding sequence set and M is the total number of transcription factors in the dataset.
In these landscapes, the regime of weakly-binding sequences and of strongly-binding sequences are separated by only a few single nucleotide substitutions.
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