In the DNA-binding segment of the protein, regions where non-specific binding residues are located will cover the regions where specific binding residues are located.
First, when the outermost L12 dimer is removed along with its binding segment of L10 CTD [ 19], CM50S tilts towards L9.
After observing the binding environments of NA-ZMR and NEU2-ZMR complexes, the interacting residues and identified binding segments of two complexes are different (RMSD of binding segments is 3.8).
Overall, the results of the present study reveal that the C-terminal PDZ-binding segment of PTEN is both necessary and sufficient for the effects of the phosphatase on spine density in this bioassay.
Sharma, A., Askari, J. A., Humphries, M. J., Jones, E. Y. & Stuart, D. I. Crystal structure of a heparin- and integrin-binding segment of human fibronectin.
The key differences between CompA and other members of the actin fold family are: (i) the presence of a cluster binding segment, the "cluster helix"; (ii) the [4Fe-4S] cluster; and (iii) the location of the homodimer interface, which involves the bridging cluster.
3) "Loop swap" experiments show that the loop between β1 and β2 of the Bub3 binding segment accounts for at least some of the differential properties of the two paralogs.
(Is this result completely new, or are there published experiments that come to the same conclusion?) 3) "Loop swap" experiments show that the loop between β1 and β2 of the Bub3 binding segment accounts for at least some of the differential properties of the two paralogs.
A sequence proposed to play a role in S-AdoMet binding, VL(E/D xGxGxG [ 36, 37], was found in GhCPS3 as ILEIGCGWG and in a more degenerate form (DxGxGxG) in GhCPS1 and 2. Given that S-AdoMet binding and methyl group transfer is the only known function shared between CPS and other S-AdoMet binding enzymes, this segment of the GhCPSs seems very likely to be involved in binding this substrate.
In contrast, most, if not all, currently identified ANK repeat-binding segments of ankyrin's membrane targets are either shown or predicted to be unstructured before binding to ankyrins (Bennett and Lorenzo, 2013).
