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Because of the high sequence conservation for the residues forming the active triad D-N-Q of EULs (Fig. 2b) a very similar binding scheme was observed in docking experiments performed with the two-domain lectin OsEULD1A (Fig. 4) and OsEULD2 (Additional file 6: Figure S3).
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A high satisfaction rate with the health insurance scheme was observed (42.1%).
The same binding pattern was observed for U36 as expected.
A single binding site was observed in the BSA rivaroxaban complex and the binding constants indicated that their binding is quite strong to be highly bound in plasma.
Similar binding mode was observed in MdOS and EGFR kinase.
No binding to BiP substrate binding domain was observed.
Robust specific binding was observed in all four brain regions tested with cortex showing the highest specific binding with a specific/non-specific binding ratio of ~18.
No binding was observed for N42A.
Minimal surface binding was observed by healthy cells.
Strong tissue binding was observed, providing a drug depot.
As expected, no binding was observed (Fig. 2).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com