Sentence examples for binding role of from inspiring English sources
Nannocystin A is a potent antiproliferative cyclodepsipeptide targeting eukaryotic translation elongation factor 1α. To elucidate the binding role of its (2R,3S -epoxide, we designed and synthesized a focused library of 10 nannocystin analogues.
The nonlinear partial differential equations to characterize spatial and temporal evolution of various species were formulated with the finite element method (FEM), and important factors for heterogeneous materials, such as ionic interactions between various species, chloride binding, role of aggregates and cracks, were discussed.
In the kinetoplastid MKPs the presence of LRRs and pseudokinase domains may replace the specific binding role of such domains.
A small set of analogues was synthesised to explore the binding role of the substituents, focusing on the nitro group and the phenols (Table 1).
Consistent with these identities, the essential binding roles of three residues (Pro-363, Pro-366, Arg-368, indicated by black boxes of Figure 3D) were previously demonstrated by mutational analyses [ 18].
To confirm the microtubule-binding role of Sec61β in a physiological setting, we monitored the levels of ER stress in C. elegans upon the expression of various Sec61β constructs.
We sought to obtain further evidence for the ligand-binding role of the ASRAH domains based on their domain architectures and predicted operonic associations.
To further investigate the membrane-binding role of native α-Syn on v-vesicle clustering, and to extend our findings to PD, we performed experiments with the three PD-related mutants A30P, E46K, and A53T.
While FPs and deletion mutants of the bottom lobe both suggest that the bottom lobe of the ATD is crucial for antibody binding, the role of the S1 domain is more ambiguous.
Given that SOCS3 is a proximal mediator associated with IL-10 ligand binding, the role of SOCS3 in O3-induced inflammation necessitates further investigation to determine its specific contribution to the adaptive/innate immune response.
Remarkably, in this case, a reverse transition to a helical secondary structure is observed after binding, highlighting the role of the membrane as a template (partitioning-folding coupling).
