Sentence examples for binding role for the from inspiring English sources

Mutations of an active site glutamate to either aspartate or alanine drastically increase the Km for homoserine, assigning this glutamate to a binding role for the α-amino group of homoserine.

These data clearly suggest a similar oligosaccharide binding role for the LysM domains found in other LysM protein families.

In addition, because our structure-function predictions led us to hypothesize a DNA-binding role for the mutated Arg, we wished to know if the R1092W mutation disrupted the ability of Zfp335 to bind to its targets in vivo.

As discussed above, the prevalence of soluble ligands such as sugars, amino acids, and metabolic intermediates for different sequence superfamilies of the clade suggested an ancestral solute-binding role for these proteins.

In this work, we propose a ribosome binding role for HflX.

We sought to obtain further evidence for the ligand-binding role of the ASRAH domains based on their domain architectures and predicted operonic associations.

In SA, only one of the two 65-amino-acid repeats of the cell wall binding region is necessary for binding, and an enhancing role for the other repeat has been suggested (Smit and Pouwels 2002).

The exonuclease activity is modulated by mutation of the helicase ATP-binding cleft and by ATP or ADP binding, suggesting a modified role for the helicase domain in the regulation of nuclease activity in these enzymes.

Her later claim is that solving the binding problem is one role for the kind of selectivity that attention enables.

Saturable AAG binding plays a critical role for the variability of total vismodegib concentration at steady state.

This observation therefore suggested that, just as for those regions bound in both cell types, direct DNA binding via established consensus motifs plays an important role for the binding of shared TFs to cell type-specific regions.