Sentence examples for binding rendering from inspiring English sources

A functional model proposes that in absence of DNA, the C-terminal region binds to the ssDNA-binding cleft, and is then displaced upon ssDNA binding, rendering it available for protein-protein interactions.

In fact, it was demonstrated that vRNPs outcompete Rab11 effectors for Rab11 binding, rendering the recycling process sub-optimal14,21 sub-optimal14,21

The inducer weakens the protein-DNA binding, rendering the mutant capable of freeing itself from non-specific DNA binding to the lac operator [48].

Under conditions of a limiting content of borate (capillary electrophoresis), agarose is reported to compete for binding, rendering the agarose interaction dominant over the DNA interaction [6].

Although the tryptophan residue in the mutant should interact with the PLP pyridine ring in a manner similar to histidine residue of the wildtype, its larger size may also occupy the space for substrate binding, rendering it unable to form a hydrogen bond with a substrate.

Conversely, antigenic variants may also reduce the strength of antibody binding rendering less sensitivity to neutralization.

There is substantial evidence suggesting that guanine nucleotide binding renders TG2 more protective [22].

However, it should be noted that the greater variability of HC3 binding renders it problematic to detect small changes, so an effect on cholinergic synaptic activity cannot be ruled out.

Our functional studies also support a role for AAA3/4 being the site of Lis1 interaction; mutation of four charged amino acids in AAA4's N-terminal helix severely impairs Lis1 binding, renders dynein nearly completely insensitive to Lis1 in motility assays, and phenocopies a Lis1 null allele in living cells.

This conformational switch also leads to the relocation of the DNA binding domains, rendering the protein unable to bind the IR1 operator site, thus allowing upregulation of qacA transcription (8).

Northumbria University has introduced a student pledge, but declined to call it an honour code or make it obligatory or legally binding – thus rendering the exercise redundant.