Sentence examples for binding regions were enriched from inspiring English sources
In summary, CTCF-A binding regions were enriched for active histone modifications and tended to appear within promoter regions.
At preadipocyte stage before adipogenesis (day 0), MLL4 binding regions were enriched with motifs of TFs functioning in various developmental lineages.
We also found that genes with NFYA-binding sites in their downstream regions were enriched among the nuclear mt genes with liver-hypo T-DMRs, and the genes with CEBPA- and STAT1-binding sites in their upstream regions were enriched among the nuclear mt genes with brain-hypo T-DMRs (Table 2 and Additional file 7).
Their regulatory regions were enriched for putative transcription factor binding sites for ISGF3, IRFs, and NF-κB.
Genes with nonsynonymous SNPs and indels within coding regions were enriched in 3′5′ cyclic nucleotide phosphodiesterase, protein kinase, ATP binding and metal ion binding activities (p-value < 0.05).
The RegionMiner and MatInspector softwares (Genomatix) were used to assess whether the two types of EWS-FLI1 specific regions were enriched in bona fide ETS factor binding sites.
In addition, these regions were enriched for RNA polymerase II and transcription factor binding sites and were located in early replicating regions of the genome.
Indeed, it has been observed that disordered regions are enriched in RNA binding proteins (Castello et al., 2012 ).
One of our most unexpected findings is that epigenetically active and repressed enhancer regions are enriched for the binding sites of two non-overlapping sets of specific TFs.
Binding regions located in the first intron of Dsp, upstream of Dsc3, upstream of the Dsg1 gene were strongly enriched in ChIP-qPCR with anti-p63 antibodies compared with control antibodies, whereas the other tested binding regions were not enriched (Fig. 5A).
