Sentence examples for binding regions that can from inspiring English sources

Exact(2)

There are 4714 SOX2 binding regions that can be mapped to TSS (transcription start site) of 3420 known genes.

The strategy developed in this study may be suitable for the initial analysis of genomic (promoter) regions extending up to 10 kb in length, revealing protein binding regions that can be further analysed using DNase footprinting [ 17, 18] and promoter activity tests.

Similar(58)

Both ends of the active center were substrate-binding regions that can specifically combine with the target RNA through the Watson-Crick base pairing.

These results indicate that HMGB1 has two LPS-binding peptide regions that can be utilized to design anti-sepsis or LPS-neutralizing therapeutics.

Although the 5' cap-dependent scanning mechanism can account for the translational initiation of most mRNAs in eukaryotic cells, several viral and cellular mRNAs contain nucleotide sequences in their 5' non-coding regions that can mediate binding of ribosomes to the mRNA, regardless of the modification state of the 5' ends.

Summary: ANCHOR is a web-based implementation of an original method that takes a single amino acid sequence as an input and predicts protein binding regions that are disordered in isolation but can undergo disorder-to-order transition upon binding.

Based upon the simplifying assumptions that mutations occur randomly, that non-synonymous changes do not occur in conserved regions, and that the fixation of synonymous mutations follows a Poisson distribution, the proportion of primer binding regions that will have three or more mismatches can be calculated based upon the rate of evolution for the gene in question between the two index species.

2) Genomic regions that contain two protein binding sites The proposed approach can also be used to refine the detection of protein binding regions that contain two or more binding sites.

In the present study, we localized more precisely this element between nucleotides −198 and −178, but we did not find any putative transcription-factor-binding site in this region that can explain the increment of the promoter activity when these 20 nucleotides were deleted.

Focusing on the LBD allowed us to compare variation in ligand binding without the confounding effects of variation in other domains, such as the DNA binding domain (DBD) and N-terminal region that can alter transactivational activity [ 5].

Structural analysis of MJ0927 reveals a positively charged region that can potentially explain its DNA-binding capability.

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