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First, TF binding regions are generally nucleosome-depleted as a result of TF and nucleosome interactions.
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Interestingly, we observed that the binding region is generally composed of multiple TGGNA motifs almost covering the full length of the sequenced region (data not shown), suggesting that higher oligomers of AbrB may interact with multiple TGGNA motifs.
Though regions containing H3K4me1 and OCRs are good candidates for enhancers, the additional binding of certain transcription factors to these regions are generally considered a reinforcement of its actual enhancer functionality [ 24].
TE-rich regions are generally heterochromatin or centromeric regions [29].
These brain regions are generally attributed to mentalizing processes.
16– 18 Though the peptide binders of Class II HLAs are generally longer, the core- binding regions are still around nine residues.
Indel-encoded regions were generally proximal to antigen binding sites.
Furthermore, among the DRAs from different species, the observed amino acid variations in their antigen-presenting regions were generally found in non antigen-binding sites (Figure 2A), indicating that purifying selection has dominated the evolution of the DRA locus.
Rural regions were generally for, and metropolitan cities against.
Suitability in Mediterranean regions is generally estimated as lower.
However, coverage for non CpG rich regions is generally poor.
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