Indeed, insertion site selection during in vitro transduction could be driven by tethering of transcription factors (TF) to specific regions according to TF binding sites location (Felice et al, 2009) and seems dependent on cellular determinants as well as on vector design (Lewinski et al, 2006).
In mouse, the strength of NANOG binding (measured by the number of ChIP-PET ditags) was positively associated with the strength of POU5F1 binding to the same region according to our re-analysis of ChIP data [ 1] (Additional file 10).
Last, we analyzed the promoter region of miR-639 by browsing the UCSC genome database (GRCh37/hg19 assembly) and found an E2F1 binding site in the promoter region according to the ENCODE ChIP-seq data.
The Central American peace treaty is in danger of being converted into a series of demands directed only at Nicaragua, rather than retaining the broad force of an accord binding on all major countries in the region, according to diplomats and Government officials here.
Under the circumstance of no differences in demographic characteristics between groups, the MDD patients with moderate-to-severe resistance exhibited higher 18F-florbetapir binding than the HCs in the parietal region according to VOI analysis.
HGB33 was provisionally assigned to the HR-1 region according to competition with HK20 and binding to the 5HB construct.
The measurement data of each region, according to the mechanism of FDG-PET, is the regional average FDG binding counts, representing the degree of glucose metabolism.
Specifically, for each studied transcription factor we obtained the set of genes with detected promoter region-transcription factor binding according to the primary study that generated binding data.
Specifically, for each studied transcription factor we obtained the set(s) of genes with detected promoter region-transcription factor binding according to the primary study that generated binding data.
This body would "not have any legally binding powers," according to a draft of the document seen by The International Herald Tribune.
