The basic region, which consists of approximately 17 amino acids and is located at the N-terminus of the domain, is a DNA-binding region that allows HLH proteins to bind to a consensus hexanucleotide E-box (CANNTG) [ 5, 6].
Dia proteins contain a RBD/FH3 region in their N-terminal part, which consists of a Rho-binding domain (RBD), 4 Arm repeats (also called Dia-inhibitory domain, DID), a dimerization domain (DD), and a putative coil-coiled region (CC, Figure 1).
Groups can contain sequence regions, which consist of start/end pairs on a specified replicon.
It consists of an extracellular ligand binding region, which is connected to the cytosolic region through a hydrophobic transmembrane domain.
Our modeling revealed that the enzymatic core is formed by a twisted, six-stranded β-sheet flanked by six helices (α1-α6) linked through a loop region to the cell wall binding domain which consists of two anti-parallel β-sheets.
157 Bazedoxifene design differed from its predecessors in its core binding domain, which consists of a 2-phenyl-3-methyl indole, a side chain effector region connected to the core binding region via a methylene hinge, and a hexamethylenediamine ring at the side chain terminus.
Egr-1 regulates gene transcription by the specific binding of its DNA binding domain, which consists of three zinc fingers, to the consensus GC-rich regions in the promoter of its target genes [11].
Even within the Ca2+-binding region of human TCTP, which consists of a stretch of 30 amino acids, only three out of 6 amino acid residues are conserved between human and plant TCTPs.
Close to this domain there is another important region in the NS5A protein, the protein kinase-R binding domain (PKR-BD), which consists of 66 amino acids and includes a 40 amino acid domain, the putative interferon sensitivity determining region (ISDR).
The C4 region of gp120, which consists of residues 416-459 (has2 numanyimportant many important functional roles.
