Sentence examples for binding region required for from inspiring English sources

To identify the binding region required for this interaction, we expressed various BAG3 mutants in HEK293 cells with αB-crystallin, and performed immunoprecipitation assays.

DNA binding is dependent upon both a zinc finger domain and an adjacent region required for cooperative binding (Mendiratta et al. 2006, 2007).

All Notch ligands share a similar architecture: a poorly characterized N-terminal requiredequired for receptor binding, a Delta/Serrate/Lag-2 (DSL) domain, a variable number of EGF-like repeats, a trans-membrane segment, and a relatively short (~100 150 amino acids) cytoplasmic tail [ 16].

With the aim of defining a minimum region required for DNA-binding activity, a series of truncated Chd1 fragments within the vicinity of residues 1010 1305 were prepared.

It was shown in [ 30] that the minimal region required for specific DNA binding includes the single zinc finger and two basic regions on either side of the ZF domain.

These results demonstrated that the miR-216a binding sequences in the BECN1-3′-UTR is the region required for the miR-216a-mediated inhibition of BECN1 expression.

This analysis revealed two regions required for binding, namely ScScc1K319-Q327 and Scc1S349-K393, bofh of which are essential for Scc1 function in vivo (Fig. 2A C).

In this study, we will employ both Y2H and GST pull-down assays to validate and determine the regions required for direct binding between AvrPiz-t and APIP12.

The Rac family proteins contain five conserved regions required for GTP/GDP binding and GTP hydrolysis.

To determine the regions required for mSYCP2 NTR binding, we co-expressed several truncations of the above candidates based on protein sequence analysis in a yeast two-hybrid assay.

Our results indicate that the loop regions required for BtR175 and BmABCC2 binding and the regions important for cytotoxicity partially overlap.