Sentence examples for binding region in both from inspiring English sources

Of particular importance is an aspartate at the identical position in the LC8 binding region in both the zebrafish and human Pak1 proteins.

We predicted disordered binding regions for interacting protein pairs by ANCHOR [ 44] and considered as features the total number of disordered binding regions, the fraction of disordered amino acids, as well as the length of the longest disordered binding region in both interacting proteins.

The DNA binding regions in both protein subfamilies show a large amount of conservation [ 17, 18], but each has distinct transcriptional targets.

Together these data provide evidence that RXR can also occupy Twist1 binding regions in limb buds, and that RREB1 can occupy Twist1 binding regions in both limb buds and PNST cells, but not ECC.

Both are mediated by an ID binding region in Med18, and the N-terminal domain (NTD) of Med11 is also disordered.

However, when comparing the UNG and MUG structures the main difference is an extra loop outside the actual binding region in UNG.

Histone modifications, chromatin structure and binding activity of EZH2 to the C/EBPβ binding region in the Vegf promoter in rat GCs undergoing luteinization.

Additionally, interaction with the phosphate binding region in the ATP-binding pocket increased potency at the cost of selectivity.

To examine the chromatin accessibility of C/EBPβ binding region in the Vegf promoter, FAIRE-qPCR was performed as described47,48 with some modifications.

These changes included decreases of H3K9me3 and H3K27me3 levels along with a decrease of EZH2 binding to the C/EBPβ binding region in the Vegf promoter all of which are associated with the activation of transcription by loosening the chromatin38.

Because not only transcription factors but also epigenetic mechanisms regulate gene expression14,15,16, we examined in rat GCs whether hCG stimulation changes histone modification levels of the C/EBPβ binding region in the Vegf promoter.