Sentence examples for binding region and then from inspiring English sources

Structural studies of E. coli Topo III revealed that the protein first recognizes the presence of single-stranded DNA through a specific DNA binding region and then induces protein rearrangements that activate the tyrosine catalytic region [35].

We then divided the X chromosome into the 559 DDC binding regions and the rest, in order to test whether the sites detected were found at a higher density in those regions.

Then, we examined whether these TFBSs showed amino acid differences in their DNA binding regions and consistent patterns in the other species S. mikatae and S. bayanus.

As there are over 300 human proteins containing at least one PDZ domain [ 16, 23], it is not clear yet whether specific recognition relies on subtle differences in the PDZ domains [ 24], on a binding region larger then the canonical, C-terminal PDZ-binding tetrapeptide [ 25], or both.

The signal-to-noise ratio was obtained by subtracting the nonspecific binding (subcortical white matter region) from the total binding (grey matter regions) and then dividing by the nonspecific binding (i.e. specific binding/nonspecific binding).

We describe the binding modes and mechanistic effects of these ligands, the closed and desensitized states of the GABAA receptor gating cycle, and the basis for allosteric coupling between the extracellular, agonist-binding region and the transmembrane, pore-forming region.

We note that AbrB possesses a strip of positive electrostatic potential encompassing its DNA-binding region and that its C-terminal domain aids in DNA binding.

The predicted binding regions can then be used for downstream analyses, such as motif discovery and annotation, to provide further functional context for the biological interpretation.

EIN3 binding regions were then associated to a gene if located within 5 kbp.

Once an ancestral sequence has been inferred, the rate of evolution from the ancestor to the target species (i.e., the number of substitutions that are fixed in the primer binding regions) is then a major determining factor of amplification success.

For example, VIRE2-INTERACTING PROTEIN 1 (VIP1), a bZIP transcription factor, rapidly enhances the expression of CYP707A1/3 by directly binding to their promoter regions and then inactivates ABA by catalyzing its catabolic pathway (Fig.  5a), finally, represses ABA responsive genes and attenuates plant tolerance to abiotic stress [ 85].