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This suggests that the endogenous Ca2+-buffers have a comparable Ca2+ binding ratio to that in Aplysia axons [25] but appear to be much more mobile.
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Both aptamers had more than 50% mol/mol binding ratio to thrombin, indicating that they are good receptor candidates for thrombin sensing applications.
Introduction of the N-terminal domain R61T mutation into apoE4 reduces the VLDL/HDL3 binding ratio to a value lower than that of apoE4 (cf. ref (14)).
By single-photon emission CT (SPECT), patient NAPO6, an Italian with ATP13A2 mutation c.G2629A, showed specific-to-nondisplaceable V′′3 binding ratios that were 75% lower in the caudate and 85% lower in the putamen than those of healthy individuals [ 24].
Indeed, all retrogene-encoded GTPases have an increased GTP/GDP binding ratio in vivo, indicating that their conformations resemble that of active GTP-bound Rap1.
The E46K variant, which overpopulates this binding mode, and the A30P and A53T variants, which elevate the SL1 SL2 ratio of binding modes relative to that of WT αS, all exhibit increased potential for this fibril-prone condition.
SUVs were used to derive SUV ratios (SUVRs) referenced to the cerebellar cortex soon after the ratio of binding in neocortex to that in the cerebellar cortex reached an apparent steady state.
A study to determine the rate of nonspecific binding between Cys-Aβ40 and non-crosslinked QD-PEG-NH2 showed an Aβ/QD binding ratio of 0.4, suggesting that approximately 7% of Cys-Aβ40 was bound to the QD surface via non-specific binding (Fig. 1b).
The specific to non-specific binding ratio (binding potential; BPND) to SERT was the main outcome measure.
It is not yet clear whether PIB will be useful for this purpose (for example, based on occipital to global binding ratios) or add value to MRI sequences that are sensitive to microhemorrhages [ 59].
In the case of a mol binding ratio of ∼5.7 1, it means that 0.32% WPI will be added in the form of gel particles.
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