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This is an effect of the low binding rate compared to the exit rate.
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Therefore, the ability of antibody to bind to the heterologous HA antigen appears to be associated with the apparent association rate compared to antibody binding to the homologous HA antigen.
Consequently, this much slower rate compared to the binding kinetics observed in Figure 1 would not contribute to the correlation data presented here.
Although methods of global blind docking are provided by most docking programs, they suffer from time-consuming execution and a low success rate compared to dockings into a known binding site.
The SPR studies gave a more detailed insight into the binding kinetics of these antibodies with the IgG unusually benefiting from an enhanced association rate compared to the Fab, but with both formats exhibiting similar dissociation rates.
Upon binding to the much larger integrin, the fluorescent tag on either disintegrin tumbles in solution at a slower rate compared to the unbound state resulting in increased levels of polarization.
Tigers seem sort of second rate compared to a lion.
Solutes from the s-block, p-block and lanthanide series with attractive solute-vacancy binding and slower reorientation rates compared to the dissociation rates show drag due to vacancy motion around the solute through alternate dissociation and association jumps.
The inflation rate compares to a 1.8percentt increase during September.
In addition, antibodies elicited to the homologous clade 2 rHA had faster association rates compared to antibody binding the heterologous clade 1 rHA.
In contrast, in MDA-MB-435 and MDA-MB-468 cells, which had relative lower transmigration rates compared to MDA-MB-231 cells, binding of the E-selectin/Fc recombinant was mainly found at sites of cell-cell contacts.
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