Sentence examples for binding proteins which play from inspiring English sources

Lamps are membrane glycoproteins that accumulate into lysosomes and late endosomes [48] and Rabs are small GTP binding proteins which play a role in regulating membrane fusion events within endocytic compartments [49].

Another example is DNA binding proteins, which play critical roles in regulating such genetic activities as gene transcription, DNA replication, DNA packaging, and DNA repair (Lewin, 2000).

Insulin-like growth factors (IGFs) are present throughout the body almost entirely in association with six specific high-affinity binding proteins, which play critical roles in the regulation of IGF action and availability [ 7].

The inhibition of mevalonate synthesis by statins results in a lesser activation of the small GTP-binding proteins, which play a key role in the activation (molecular on/off switches) of intracellular inflammatory signalling pathways.

These genes encode a family of neural specific, zinc-finger-containing DNA-binding proteins, which play a role in the development of the nervous system.

These are intracellular metal-binding proteins which play a significant role in the regulation of essential metals [ 104].

The fourth example is lipid-binding proteins, which play important roles in cell signaling and membrane trafficking (Downes et al. 2005), lipid metabolism and transport (Glatz et al. 2002; Haunerland and Spener, 2004), innate immune response to bacterial infections (Bingle and Craven, 2004), and regulation of gene expression and cell growth (Bernlohr et al. 1997).

Kindlin-1 is an integrin binding protein which plays a key role in regulating integrin activity [16].

S100A14 has been reported to be able to interact with nucleobindin (Calnuc) in a yeast two-hybrid system, a Golgi calcium binding protein which plays a key role in the constitution of calcium storage [22].

Yeast also contains an ACB1 -encoded acyl-CoA binding protein, which plays an important regulatory function in delivering acyl-CoA into various pathways (Schjerling et al. 1996; Gaigg et al. 2001; Faergeman et al. 2004; Rijken et al. 2009).

Considering NLC1-C's roles in the control of cell proliferation and apoptosis, Nucleolin, an RNA-binding protein which played a critical role in tumorigenesis and angiogenesis, was chosen for further studies.