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The authors perform mass spec of mutant-p53 interacting proteins in normal and tumor cells and (in addition to reporting the entire list of mutant p53 binding proteins, which is important) they show that BAG2 is a major binder.
CSDA is a member of the highly conserved Cold Shock Domain family of DNA binding proteins which is involved in post-transcriptional control of gene expression [ 42, 43] and was up regulated.
This suggests that Mcm1 tends to collaborate with some non-specific binding proteins, which is consistent with the fact that Mcm1 is a cofactor of multiple TFs (Dolan et al., 1989; Jarvis et al., 1989; Keleher et al., 1989; Mead et al. 2002).
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Plant lectins are carbohydrate binding proteins which are reported to be toxic to several plant pathogens [ 38].
Early phase was associated with dramatic up-regulation of structural and metal binding proteins, which were repressed in later phases.
SP1 and SP3 are ubiquitously expressed CACC-box binding proteins, which are dominant in ES cell nuclear extracts.
These two cellular proteins are small DNA binding proteins, which are able to modify DNA structure at the site of integration and increase the probability of integration.
The ligand binding domain is considered to have evolved from prokaryotic periplasmic binding proteins which are involved in amino acid and nutrient transport in bacteria [ 26].
Specificity protein 1 (SP1) belongs to a family of universally expressed zinc-finger DNA binding proteins, which are involved in transcriptional regulation of a variety of genes.
The biological function of IGF peptides are also modulated by a family of IGF binding proteins, which are found in the circulation and in the extracellular fluids.
Another group of importance was composed of uterine genes encoding ion binding proteins, which are essential for the mineral phase interactions during eggshell calcification.
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