Your English writing platform
Discover LudwigExact(1)
We have used a short-hairpin RNA (shRNA) library in a lentiviral vector that contains ≈5000 shRNAs designed against genes encoding kinases, phosphatases, tumor suppressors and DNA binding proteins to perform a loss-of-function screen to identify genes causing dFdC resistance in HeLa cells when their expression is decreased.
Similar(59)
Products of the large helicase genes may act in concert with the single-stranded DNA-binding proteins to perform an equivalent function to that of TraI, which is bifunctional, possessing relaxase activity and catalysing a processive 5′- to 3-′ helicase reaction that provides the motive force for strand transfer.
Mutating the partially buried Phe254 residue was better tolerated and yielded enough metastable protein to perform a limited binding study by fluorescence anisotropy.
Having established its location at the invasive apical end of the merozoite and homology with other known RBC binding proteins, we performed assays to determine whether native PfRH5 binds to RBCs.
These binding proteins may perform functions extracellularly (e.g. in plasma) or transport these agents; to the nucleus to interact with nuclear receptors (principally PPARs and retinoic acid receptors 16) or for interaction with metabolic enzymes.
To assess the function of this gene, a screen of binding proteins was performed, which showed that G72 binds to and activates d-amino acid oxidase.
These structurally diverse groups of B12 binding proteins perform various important biological activities, both by transporting B12 as well as catalyzing various biological reactions.
(v) Would other RORE binding proteins perform circadian pacemaker function?
As an effort to characterize the few candidate genes (here in Nedd4) identified by Y1H as well as its associated N4bp3 (Nedd4-binding protein), we chose to perform similar candidate EMSA assay using Nedd4 antibody.
To understand the major functional roles of the cancer-associated 14-3-3 14-3-3 14-3-3ins, we performed Gene Ontology and KEGG-pathway enrichment analysis and clustered the significantly enriched terms using the DAVID Functional Clustering tool, which groups terms bindingn the assumproteinsat annotations attached to similar sets of genes are likely to be related to each other (32).
Gene Ontology analysis and PFAM domain analysis of RNA binding proteins was performed with DAVID [ 29] using as a background a universe of gene list of all proteins spotted on the microarray and Benjamini-Hochberg correction of the p value.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com