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CUG-BP1 was one of the first CUG binding proteins to be associated with DM1 [11], but although its level increases in DM1, it has not been detected in the nuclear foci [12], [13].
This storage pool was shown to be surrounded by lipid-droplet binding proteins, to be flexible in size and to become smaller during absorption [7].
Further, the recent high resolution structure of the yeast mt-LSU also describes 5S rRNA and associated binding proteins to be absent [31].
Here the cap-column serves as a molecular mimic for the mRNA 5´-cap allowing eIF4E and associated binding proteins to be isolated from cell lysates.
Ruan and Ying [ 48] suggest that this change in IGF binding proteins could be an initiating factor in IPF and Veraldi and Feghali-Bostwick [ 49] propose IGF binding proteins to be central mediators of fibrosis.
Although we found gene sets related to metal ion or cation ion binding proteins to be affected, we did not detect an enrichment of gene sets connected to the described effects resulting from ion substitution.
Similar(53)
The drug could then 'piggy-back' on this native binding protein, to be released preferentially in the tissue of interest.
In conclusion, we report the identity of a ∼ 45 kDa imidazoline binding protein to be brain creatine kinase and this enzyme possesses an I2 binding site.
Modifications to zinc-finger binding specificity have recently enabled custom DNA-binding proteins to be designed to a wide array of target sequences.
This technology has rather evident potential advantages: unlimited number of carbohydrate ligands coated onto one small sized chip, enormously low consumption of both carbohydrate ligands and carbohydrate-binding proteins to be tested, etc. Literature data demonstrate that three approaches are used for glycoarray design.
Using the same arsenic affinity chromatographic strategy, Menzel et al. identified two arsenic-binding proteins to be tubulin and actin on the basis of their molecular weights.
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