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A kinase anchoring proteins (AKAPs) are PKA binding proteins that localize PKA and other signaling molecules to discrete sites in many cells including neurons.
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Less is known about NRP1, an RNA binding protein that localizes to stress granules and has not been related to polarity before (Buchan et al., 2008).
A significant subset of these genes encoded proteins that localized to the extracellular space and had collagenase or hyaluronic acid binding activities.
A similar Golgi expansion phenotype was seen in NRK cells following knock down of TMF/ARA160, a Rab6-binding protein that localizes to the Golgi [23].
Rfa1 is the largest subunit of the yeast replication protein A (RPA) complex, a single-stranded DNA-binding protein that localizes to sites of DNA damage and stalled replication forks.
Patellins are a six member family of membrane proteins in Arabidopsis, PATL1, the best characterized patellin, is a phosphoinositide-binding protein that localizes to the expanding and maturing cell plate [ 68], however little information is available regarding PATL3 and its possible role in phloem physiology remains to be elucidated.
In this report evidence is provided that NDRG1 is a Rab4a effector protein that localizes to perinuclear recycling/sorting vesicles in the Trans Golgi network by binding to phophatidylinositol 4-phosphate and is involved in recycling of E-cadherin.
Cdc13 is a single stranded telomere binding protein that specifically localizes to the telomere ends of budding yeasts and is essential for cell viability.
Because methyl-FoxO3 is localized to the chromatin under after serum starvation and LY294002 treatment, we asked if binding proteins that are known to bind to methylated histones could interact with the methylated fraction of FoxO3 (Fig. 6).
GRSF1 (G-rich sequence factor 1) is an RNA binding protein that was previously reported to localize in the cytosol.
Dis1 is a microtubule binding protein that is required for the proper attachment of kinetochore microtubules to the kinetochores, and is localized at the kinetochore specifically during mitosis [3], [4].
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