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Both C/EBP and GCN4 are sequence-specific DNA binding proteins that control gene expression.
The actin binding proteins that control filament assembly are therefore attractive targets for those who wish to reorganize actin filaments and reengineer the cytoskeleton.
Transferrins are iron binding proteins that control the level of free iron in biological fluids, especially in the blood plasma [ 1].
DOI: http://dx.doi.org/10.7554/eLife.02978.012 Small GTPases are guanine nucleotide binding proteins that control a variety of essential cellular functions (Vetter and Wittinghofer, 2001; Cherfils and Zeghouf, 2013).
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PARP1 expression/activation in glial cells allows the function of transcription factors such as nuclear factor- κB, activator protein-1 and cAMP-response element binding protein that control cell proliferation and inflammatory responses.
Histones have the basic DNA-binding proteins that control multiple aspects of DNA function [ 14].
S100 proteins are low molecular weight (9 to 14 kDa) intracellular calcium-binding proteins that control key cellular pathways.
Complexes formed both in the nucleus and the cytoplasm were examined because for some RNA elements it has been suggested that the RNA-binding proteins that control their cytoplasmic activity are pre-loaded in the nucleus.
S100 proteins are low molecular weight (9 to 14 kDa) intracellular calcium-binding proteins that control key cellular pathways including regulation of the cytoskeleton [ 1], cell migration and adhesion [ 2], and host oxidative defense [ 3, 4].
RUNX are context-dependent enhancer-binding proteins that control transcription of master-regulatory genes in Drosophila and mammals, co-operating with TCFs (e.g., in the TCRα enhancer; Figure 6A), but also with other signaling inputs including TGF-β/SMAD and Notch (Canon and Banerjee, 2000; Chuang et al., 2013).
The raptor mTOR complex signals to its downstream effectors S6 kinase/ribosomal protein S6 (p70S6K) and the eIF4E-binding protein (p4E-BP1) to control transcription and translation, which selectively regulates multiple proteins that control cell cycle and apoptosis (Gibbons et al, 2009).
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