Sentence examples for binding proteins responsible for from inspiring English sources

Indeed, recent work suggests the primary role for Cyc8 Tup1 involves obstructing the activation domains of the DNA binding proteins responsible for its targeted recruitment [23].

To find RNA binding proteins responsible for modulating splicing during cancer progression, we can identify stage-dependent splicing pattern changes based on the ratio of alternative spliced isoforms and search for overrepresented nucleotide sequences near stage-associated splicing events.

In many of these cases, OP-1 modulated the expression of not only the ligands, but also their receptors, mediators of downstream signaling, kinases responsible for an activation of the pathways, binding proteins responsible for the inhibition of the pathways, and transcription factors that induce transcriptional responses.

Which are the CUn-MepG binding proteins responsible for gene activation?

The gene, hasG, not present in the A. terreus cluster, encodes for an FAD binding protein responsible for converting a prenyl to a methylbutadienyl side chain to produce hexadehydroastechrome from astechrome.

Additionally, a specific heme binding protein responsible for transporting the ingested heme directly to the hemosome for detoxification has been identified in the cattle tick Rhipicephalus microplus (Lara et al. 2005).

In addition to tau, tubulin, CEP164, CEP97, and autophosphorylation, TTBK2 has also recently been found to phosphorylate transactive response (TAR) DNA-binding protein 43 [ 40], or TDP-43, a DNA/RNA binding protein responsible for transcriptional repression, pre-mRNA splicing, and translational regulation [ 88].

Heterogeneous nuclear ribonucleoprotein A2/B1 (HNRNPand1) and heterogeneous nuclear ribonucleoprotein C (HNRNPC) are two abundant nuclear RNA-binding proteins responsible for pre-mRNA processing36.

Not only telomere length per se but also disruption of the associated telomere-binding proteins responsible for the three-dimensional loop structure can induce chromosomal instability, senescence or apoptosis.

By microarray analysis, we observed in mono-transgenic mice a downregulation of members of the S100 protein family, small calcium-binding proteins responsible for a wide range of intra- and extracellular functions [ 39].

K-ras encodes a low-molecular weight GTP-binding protein responsible for transmitting signals from receptor tyrosine kinases to downstream modulators of cell growth and survival [5], [6] and has been shown to stabilize the MYC protein [7].