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DNA binding proteins may recognize sequences that are similar to their real target sites giving rise to non-specific interactions ([31] and references therein).
Two of the well characterized DNA binding proteins TNPA of En-1 and TNP1 of Tam1 shared little similarity and it was suggested that non-homologous DNA binding proteins may recognize diverse subterminal DNA-binding motifs [ 32].
Similar(58)
One could speculate that a mitophagy adaptor or other phosphoUb binding proteins may preferentially recognize the UbretraCT conformation of phosphoUb, and it will be interesting to identify such proteins.
Methyl cytosine binding proteins (MBPs) may recognize and bind to methylated DNA.
Clearance of cytokine binding proteins may be important in the resolution of inflammation.
These binding reagents may recognize bait proteins directly or affinity tags that are fused to bait proteins.
Mimicry of the action of calcium-binding-protein may prove useful for future drug discovery.
Systematic pair-wise comparison of the staurosporine-binding site of the proto-oncogene Pim-1 kinase with 6,412 druggable protein-ligand binding sites suggested that the ATP-binding site of synapsin I may recognize the pan-kinase inhibitor staurosporine.
Specific and non-specific DNA binding proteins recognize sequence-dependent DNA shapes [5].
Each L. biflexa replicon encodes its own partition proteins from origin-proximal genes that may recognize and interact with a replication-specific binding site.
Moreover, this mechanism may provide an answer to the fundamental question of how lipid-binding proteins generally recognize the various lengths of simple alkyl chains.
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