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Because Cl-, Na+, K+ and Ca2+ channels were implicated to modulate sperm function [ 37- 41], ion binding proteins may play crucial roles in post-translational regulation in sperm.
However, it does not rule out that splicing factors, in addition to other RNA binding proteins, may play a direct role in controlling PA choices.
In mammals, there is considerable evidence suggesting that methyl-CpG binding proteins may play a significant role in histone modification through their association with histone deacetylases [ 7- 11].
Our findings suggest that the sequestration of hnRNP-H and other RNA binding proteins may play a mechanistic role in neurodegeneration associated with the C9ORF72 mutation.
In mammals, there is evidence suggesting that methyl-CpG binding proteins may play a significant role in histone modification through their association with modification complexes that can deacetylate and/or methylate nucleosomes in the proximity of methylated DNA.
It is interesting to note that FST expression was increased in the stromal cells of FIB, while FLRG was up regulated in IDC, indicating that the two activin binding proteins may play diverse roles in tumor progression.
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There is growing awareness that RNA-binding proteins may play an important role in clock function.
This suggests that some RNA-binding proteins may play a role in the behavior of these gene classes.
These data suggest that renal lead-binding proteins may play a role in mediating known alterations in renal gene expression associated with formation of intranuclear inclusion bodies.
It is important to note that although D1 is an obvious candidate given its binding properties, it is likely that other DNA-binding proteins may play an important role in this model.
In addition, calcium and calcium-binding proteins may play some roles in the regulation of early wound responses by elevating intracellular calcium levels and changing the phosphorylation patterns of proteins [ 50].
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