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Analysis of known protein-DNA complexes suggests that many other DNA binding proteins could be designed in a similar fashion.
One potential mechanism promoting similar evolutionary rates of physically binding proteins could be similar fractions of residues involved in protein-protein binding.
To test whether the sensor kinase and carbohydrate binding proteins could be exported from the cell, portions of the genes encoding the N-terminal segments of LevQ (up to Asp202), LevT (up to Asp72) or LevS (up to Ile253) were fused to the ΔSPNuc sequence (Figure S4), which encodes a nuclease derived from Staphylococcus aureus that lacks its export signal [15].
Thus listed putative nucleic acid binding proteins could be part of the ticks system to modulate host inflammation response to tick feeding activity.
Activation of metal binding proteins could be accounted for the role of ions (particularly calcium) in multiple pathways of gene expression regulation in the brain [ 26].
As hypothesized for other known lncRNAs, specific transcriptional factors, able to act as both RNA and DNA binding proteins, could be involved in forming a molecular platform in chromatin contexts.
Similar(52)
In fact, in this article we will consider a positive PWM hit to match any protein with the family (i.e. a positive hit for a STAT1 binding protein could be a PWM for STAT3).
Differential expression of glycans or glycan-binding proteins could be capitalized for the identification of novel biomarkers and might provide novel opportunities for therapeutic intervention.
In this respect, side-binding proteins could be thought of as allosteric regulators of actin filament kinetics.
This approach demonstrated that arsenic-binding proteins could be identified in the presence of a large excess of nonspecific proteins.
Methods to identify RNA-binding proteins could be divided into two categories: recognition from protein structure and prediction from amino acid sequences.
More suggestions(15)
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