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Mechanisms that regulate PKC activity, including phosphorylation and interaction with isozyme-specific binding proteins, are also potential therapeutic targets.
Lipid binding proteins are also involved in pollen-pistil interactions.
Since TGFβ1 is a strong promoter of the EMT, a critical step in carcinogenensis, we verified whether S100 calcium binding proteins are also involved in this process.
Presence of chromatin remodellers, chromatin-associated proteins, and methyl DNA binding proteins are also important for structural modification of chromatin [ 4, 39, 40].
Second, apart from kinases/phosphatases as previously reported, ion binding proteins are also enriched in sperm, underlying the crucial roles of intracellular ions in post-translational regulation in sperm.
Lectins (carbohydrate binding proteins) are also involved in immune function through the lectin-complement pathway, in which the mannose-binding lectin recognises infectious agents and triggers PO activation [ 75, 76].
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Various isoforms of histone proteins along with other nucleic acid binding proteins were also detected.
Other than uncharacterized proteins, genes encoding putative short chain dehydrogenases and periplasmic binding proteins were also among the most prevalent functions for proteins with predicted Tat signal sequences.
It is highly likely, however, that the ability to cross-link other DNA binding proteins is also limited by the intrinsic temporal constraints on crosslink chemistry.
Interestingly, all microcystin binding proteins were also found to be differentially expressed in the previously performed proteomic study (Table 1) indicating that microcystin binding to proteins may at least partly explain the differences in the abundance of these proteins.
In addition, transcripts encoding nucleic acid binding and DNA binding proteins were also significantly enriched.
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