However, as Dact proteins are shared binding partners of both Dvl2 and Sestd1,, it remained possible that the Sestd1-Dvl2 complex formation observed in these cells might occur indirectly via mutual binding to endogenous Dact proteins.
Although the PCA classification yielded fairly distinct classes, binding of several of the 42 proteins are shared between some classes.
PI4P binding proteins are well described in several pathogenic bacteria such as the SidC and SidM proteins from Legionella38.
Some molecular functions (e.g., histone lysine acetyltransferase activity) of known CM domains are relatively unique to CM, but many others (e.g., protein kinase activity and DNA binding) are shared by a broad variety of different biological processes.
Some genes were shared by different pathways, such as CD74 antigen in the immune effector process, in antigen processing and presentation, in inflammatory response and in cytokine binding; CCAAT/enhancer binding protein beta (CEBPB) was shared in pathways of the immune response, in defence response and in inflammatory response.
Testis-brain RNA-binding protein, a testicular translational regulatory RNA-binding protein, is present in the brain and binds to the 3′ untranslated regions of transported brain mRNAs.
A hypothesis to be evaluated is that ankyrin-binding activity is shared by all of these proteins.
This study also suggests that the RNA-binding argonaute protein family, which is shared among eukaryotes, most archaea, and at least some bacteria (such as Aquifex aeolicus), is homologous to and originally evolved from components of the translation initiation system.
No Vn-binding proteins were detected in the weak Vn-binding strain KR497 (data not shown).
The PxIxIT calcineurin-binding motif of NFATc is shared by several other peptides and proteins binding to calcineurin.
