Indeed, many genes involved in photosynthetic pigment biosynthesis along with pigment-binding proteins such as chlorophyll a/b binding proteins were discovered to be upregulated in our genome-wide profiling of green curd cauliflower.
Subfamilies of widely distributed bacterial GTP-binding proteins were discovered by the Escherichia coli (E.coli) Era and the Bacillus subtilis (B.subtilis) Obg (BsObg) proteins [1], [2], [4].
The p53 protein was discovered in 1979.
CtBPs (C-terminal Binding Protein) were initially discovered as proteins binding to the C-terminal domain of adenovirus EA-1 [ 23].
The oncogenic CtBPs [C-terminal (of E1A) binding protein] were discovered through their interaction with the C-terminus of the E1A protein from adenovirus (Boyd et al., 1993).
Re "Two Paths to the Same Protein" (Business Day, March 28): Genes and proteins are discovered, not invented.
Virus-binding proteins, which were discovered from a bacterial culture derived from activated sludge [ 14], could be alternative viral adsorbents, because these bacterial proteins can stably interact with human viral particles [ 15].
Methyl-CpG binding protein 2 (MECP2) was discovered as a protein that selectively binds methylated DNA [ 1].
Another example of a tract binding protein has been discovered in D. discoideum, where some 200 copies of terminal repeat retrotransposons are under transcriptional control by a 134 bp DNA control element [ 59].
In the late 1990s, it was discovered that transcription was repressed when methyl CpG binding proteins were recruited to methylated CpG islands (Hendrich and Bird, 1998).
In our previous transcriptomic analyses of the laser-capture microdissected GBM vessels, the insulin-like growth factor-binding protein-7 (IGFBP7) was discovered as a highly upregulated selective biomarker of GBM vessels (Pen et al, 2007).
