Other putative DNA binding proteins are predicted to be involved in transcriptional regulation.
Ten calcium binding proteins were predicted to be myristoylated in Arabidopsis, including five members of the copine family and five calcineurin B-like proteins, at least one of which (SOS3) has been shown to activate an SnRK family kinase [ 11].
In both Gb3 and GM3, the apolar side of the central galactosyl group has a similar orientation to that in GalCer (Fig. 3a c); thus, GalCer-binding proteins are predicted to also bind to Gb3 and GM3 through CH π stacking.
In a study of Butyrivibrio proteoclasticus, 12 ABC transport system substrate-binding proteins were predicted to function as carbohydrate transporters [ 80].
All extracellular and cytoskeletal proteins are listed in Figure 3 source data 1, 2. Nucleic acid-binding proteins are predicted in silico based on presence of DNA-binding domains (DBDs) and RNA-binding domains (RBDs).
The nonspecific binding value of sirolimus to microsomal protein was predicted to be 0.45 using log P (4.3, http://www.drugbank.ca/drugs/DB00877) and the microsomal concentration (0.4 mg/ml) according to the in silico method by Hallifax and Houston.
Interfering with the binding of FIH to ARD-proteins is predicted to increase HIFα CAD-hydroxylation, whereas interfering with AR-hydroxylation by FIH is predicted to decrease HIFα CAD-hydroxylation.
For example, 21 of these 39 proteins are predicted substrate-binding components of ABC transporters used for importing sugars, amino acids/peptides, and metals.
Two of these proteins are predicted microtubule associated proteins and another is an intra-cellular GTP-binding protein.
Based on a bioinformatics analysis, FK506-binding protein 51 (FKBP51) was predicted to be a target of miR-100 and miR-99a (Bhushan and Kandpal, 2011).
