At the time of its identification, no RNA binding protein was identified as a partner of the HP1 protein family.
Using RNA affinity chromatography and mass spectrometry the binding protein was identified.
The E2A 54.9 kDa DNA binding protein was identified on the complementary strand between nucleotides 21305 and 22777.
In addition to PGRPs, a transcript encoding a putative gram-negative bacteria binding protein was identified and named PperGNBP [GenBank: EZ617706], cluster 301, transcript 5' truncated.
The rat MIF binding protein was identified as the acute phase protein α-1-inhibitor 3 [ 27]. α-1-inhibitor 3 is a rodent member of the α-2-macroglobulin protease inhibitor family that is found in high concentration in serum [ 28].
Likewise, several isoforms of selenium binding protein were identified, but all found to have low protein levels in inflamed mucosa compared to non-inflamed tissue.
First, deleterious mutations in ybgI a cytoplasmic metal ion binding protein were identified in both non-tobacco adapted lineages (F009 and G002)(Additional file 1: Table S3 – marked by §).
Although cellular effects of 1,25(OH)2D3 traditionally have been attributed to activation of a nuclear vitamin D receptor (VDR), a novel receptor for 1,25(OH)2D3 called 1,25D3-MARRS 1,25D3-MARRSsociated, rapid response steroid-binding) protein was identified recently.
Furthermore, no intracellular DUES-binding protein was identified, and DUESs show no orientation bias around the chromosome [13] [15] features expected from a sequence that interacts with the replication machinery.
Interestingly, a sole oligosaccharide ABC transporter-specific ATP-binding protein was identified in the genome and found to be constitutively highly expressed, consistent with a single ATP-binding protein energizing multiple oligosaccharide ABC transporters as previously described [ 56].
Furthermore calcyclin, a Ca2+ ion-binding protein, was identified by proteomic analysis to be significantly upregulated when treated with simvastatin and it has been suggested that this protein plays an important role in the anabolic effect of simvastatin on bone [ 27].
