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The drug could then 'piggy-back' on this native binding protein, to be released preferentially in the tissue of interest.
In conclusion, we report the identity of a ∼ 45 kDa imidazoline binding protein to be brain creatine kinase and this enzyme possesses an I2 binding site.
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This storage pool was shown to be surrounded by lipid-droplet binding proteins, to be flexible in size and to become smaller during absorption [7].
Further, the recent high resolution structure of the yeast mt-LSU also describes 5S rRNA and associated binding proteins to be absent [31].
Here the cap-column serves as a molecular mimic for the mRNA 5´-cap allowing eIF4E and associated binding proteins to be isolated from cell lysates.
Ruan and Ying [ 48] suggest that this change in IGF binding proteins could be an initiating factor in IPF and Veraldi and Feghali-Bostwick [ 49] propose IGF binding proteins to be central mediators of fibrosis.
The above findings support a role for the first RNA-binding protein to be identified as part of a functional calicivirus RNP complex and give further insight in the molecular mechanism used for genome translation and replication by this important group of pathogens.
We found transcript levels of the chlorophyll a/b-binding protein to be downregulated during stress.
The most notable of these is the tumour suppressor pRb, which was the first E1A-binding protein to be identified.
Modifications to zinc-finger binding specificity have recently enabled custom DNA-binding proteins to be designed to a wide array of target sequences.
Among the many Ca(2+)/CaM-binding proteins to be discovered, the multifunctional protein kinases CaMKI, II, and IV play pivotal roles.
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