Sentence examples for binding properties of individual from inspiring English sources

Such methods, similar to the more common structure based methods [57, 58], generally do not allow precise (e.g. binding constant error <10-fold) prediction of binding properties of individual compound-target interactions, but they do provide guidance to focus efforts on compound classes or libraries with the best chances for success [59 64].

Peptide scrambling or amino acid replacement are most commonly implemented if the binding properties of individual amino acids is known.

Binding properties of individual peptide-phage clones were tested in a phage-ELISA format as described [70].

However, the technological advances that have made it possible to generate long lists of candidate peptides have far outpaced our ability to characterize the binding properties of individual peptides.

This suggests that the DNA-binding specificity of tetrameric p73 is determined by the DNA-binding properties of individual DNA-binding domains, whereas the absolute affinity depends on the oligomerisation equilibrium.

Determination of the structures and binding properties of Bcl-2 family proteins has been a fruitful tool in delineating biological roles and the role of individual Bcl-2 proteins and their viral counterparts.

This demonstrates that individual features of the native and hydroxylated estrogens determine the specific binding properties of the compound within the binding site of the human UGT1A10 and the mutants.

Due to the reported dependency of binding properties of the second-generation TSPO ligands on a genetic polymorphism of the TSPO gene, all individuals were genotyped and classified as low-, medium-, or high-affinity binder (LAB, MAB, and HAB) [14 17].

In order to understand the contributions of individual amino acid residues to this complex binding mode, N-terminal deletions and point mutations have been introduced, and the binding properties of each mutant inhibitor protein have been examined.

Saturation binding studies were carried out to analyse the in vitro binding properties of the diabody.

Since the binding pockets of mutants have different amino acids available, the binding properties of compounds may differ.