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We present a multi-objective optimization of the binding properties of a molecularly imprinted polymer (MIP) which specifically binds glucuronic acid (GA).
Cu II) binding properties of a cytochrome c with a synthetic metal-binding site: His-X3-His in an α-helix.
We applied molecular dynamics simulations to investigate the binding properties of a designed ankyrin repeat protein, the DARPin CD4 complex.
In the present study we have analyzed the binding properties of a set of previously identified natural ligands for HLA-DQ2, the primary disease predisposing allele.
Such a protein hybridization technique will be generally applicable to change the ligand binding properties of a variety of ligand-inducible functional proteins.
The present study aimed at investigating the binding properties of a set of 23 fibrates, characterized by similar carboxylic heads but differing in the size and orientation of the hydrophobic portion, using computational approaches.
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Yan et al. (2014) reported the regulation of 1O2 production probe using the binding properties of an aptamer (AP).
However, following gene duplication, the binding properties of an OR gene (or any receptor) may be modified by a few changes to the binding site.
In other words, we predicted the binding properties of an amino acid (the target site) taking into account all the amino acids in the chains.
The binding properties of an aptamer are dictated by its sequence and the deriving folding into stem-loop structures [ 13, 17].
Since both BMP2 and Activin A utilize the type II receptors ActRII and ActRIIb, we hypothesized that a chimeric ligand that possesses the type I receptor specificity of BMP2 together with the high affinity type II receptor binding properties of Activin A may have enhanced BMP2-like properties.
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