Sentence examples for binding propensity for the from inspiring English sources

The binding propensity for the 20 amino acid residues and 4 nucleotides present in protein-RNA complexes has been calculated using following procedure [ 21- 23]: (i) We computed the frequency of occurrence of amino acid residues (nucleotides) in binding sites (fb) and in the protein (RNA) as a whole (ft).

Earlier structural studies observed a tighter binding propensity for single-stranded DNA relative to single-stranded RNA guide strands in pPIWI proteins [ 21, 22].

This is most likely because those types of amino acids are abundant in RNA-binding sites and show the highest binding propensities for RNA-protein interactions.

On the basis of binding propensity at the different pockets and inhibitor constants, we ranked these isomers as potential candidates for the HCV inhibition.

(ii) The binding propensity was normalized with the percentage of binding site residues in the considered protein-RNA complexes.

AUC can be directly computed from the estimated CaM binding propensities when using the Discriminant function scoring approach.

The results of computational analysis are in good consistence with the experimental data and the present findings suggested that HTMF exhibits a good binding propensity to BSA protein which will be helpful for the drug design.

We have evaluated the influence of RNA base sequence on the binding propensity of amino acid residues in nucleotides.

Hence, vascular drug particle design needs to be tailored to account for higher binding propensity at larger bifurcation angles.

Interestingly, we noticed few differences in the binding propensity of residues among different organisms.

Consequently, the binding propensity measures and nonbinding propensity measures were adopted in this study, which were made based on the prediction results of RNA-binding residues and nonbinding residues, respectively.