Sentence examples for binding profiles suggests that from inspiring English sources
Specifically, we show this for a particular chromatin state, the Pc silenced state, but the overall similarity of the Ubx and Hth binding profiles suggests that, in general, chromatin state may exert a strong influence on transcription factor binding.
The ALKBH3 genomic binding profile suggests that ALKBH3 is an intrinsic DNA repair protein that removes DNA alkylation that might occur naturally during transcription [ 63, 66].
A heat map was constructed from the median normalized fluorescent data and in each case the synbody produced a unique binding profile suggesting that each synbody behaves as a unique binding entity (Figure 5A).
These binding profiles suggest a link between H4K16 acetylation and the MSL HAT complex.
In general, the genome-wide binding profiles of Ubx and Hth in embryo chromatin appear quite different from the imaginal disc profiles, suggesting that target selection by these proteins undergoes a widespread developmental reorganisation.
IRP1- and IRP2-overexpressing tumours exhibited distinct gene-expression profiles, suggesting that IRPs may differentially modulate cancer growth by mechanisms independent of their function as IRE-binding proteins.
Analysis of the promoters of Ash2L regulated genes, identified by transcriptional profiling, suggests that a handful TF binding sites are moderately enriched, among which the CCAAT box.
These evolutionary conserved binding profiles further suggest that the function of the MSL and NSL complexes in transcriptional regulation are also conserved between Drosophila and vertebrate cells.
The predicted H-NS binding profile of CAP suggests that it too is able to repress hypervariable regions including polysaccharide biosynthesis gene cassettes, a Type III restriction-modification system and a CRISPR locus (Figure 3, Table S3).
Moreover, the multi-receptor binding profile of pasireotide suggests that it may be effective in patients with acromegaly resistant or refractory to octreotide.
Integration of the protein expression profiles of different tad-locus mutants [15] and our IL-1β binding data suggests that decreased expression of RcpA might lead to increased binding of IL-1β.
