Sentence examples for binding profiles such that from inspiring English sources

It is often the case that TFs belonging to the same structural classes share similar DNA binding profiles, such that distinct TFs of the same class may bind to similar sequence patterns.

Basically, the σ1 receptor is believed to have a ligand binding profile such that -benzomorphans are at least fivefold to tenfold more potent than their corresponding -isomers [7].

DamID assay using INM proteins such as Emerin yielded binding profiles that were similar to Lamin B1 [ 14], indicating that the identified genomic regions largely represent those regions that are preferentially positioned to the nuclear periphery.

One such example is the polycomb binding profiles that were previously generated for the CRC cell line SW480 and used as a model of differentiated cells.

While parental H5 HA exhibited limited binding to human tracheal epithelium, introduction of selected mutations converted the binding profile to that of a current human influenza strain HA.

However, the G228S mutant showed an expanded binding profile that included binding to non-ciliated cell types in addition to ciliated cells (Figure 3H).

The DNA binding domain of p53 also has a complex, distinctive binding profile that is different from the profiles when binding to p53BP1 and p53BP2 [ 62].

Paliperidone is another new antipsychotic agent with a binding profile similar to that of risperidone.

The binding profiles obtained showed that the VEGF binding integrity was visually indistinguishable for D7 and D28 samples compared to D0 samples (Fig. 5A,B).

Peri-centromeric heterochromatin displays a protein binding profile and epigenetic environment that is clearly different from that of centromeric cores.

ABT-737 and ABT-263 (its more-soluble clinically applicable analogue) both display binding profiles similar to the BH3-only protein BAD, such that they bind BCL-xL, BCL-2 but not MCL-1.