Your English writing platform
Discover LudwigExact(1)
When binding profiles for additional TFs become available, more putative regulatory elements will be detected, which in turn can be validated for functionality.
Similar(59)
Thus, defining the in vivo binding profile for additional cell-specific regulators of cardiogenesis should vastly improve cell type-specific predictions, as we observed.
Our approach of computational promoter analysis was limited by the availability of experimentally determined TF-binding sites for deriving binding profiles of additional TFs.
(b) ChIP-seq binding profiles for Med1, Smad3 and PU.1 at the locus of Foxo1 gene.
Julia Zeitlinger, Alexander Stark and colleagues report genome-wide binding profiles for the transcription factor Twist across six Drosophila species.
Thus, we compared binding profiles for these proteins over 10 kb regions centered around insertion sites of reference transgenes which were mapped to the interbands studied and used to clone respective DNA sequences (Additional file 1 Figure S1, Additional file 2 Table S1).
At present, there are no successful algorithms capable of predicting binding profiles for novel proteins.
We plotted the nucleosome occupancy and Htz1 binding profiles for citrate cycle and ribosome genes.
The binding profile for CBM42 was very distinct as compared to the other probes, with a consistent binding of all Palmaria palmata extracts (Fig. 3), which cell walls contain almost exclusively mixed-linkage (1,3), 1,4 -β-xylan (MLX)27.
Strikingly, the p73 binding profile is indistinguishable from the previously described binding profile for p63 in the same cells.
The PWM score thresholds for the studied TF binding profiles are provided in Additional file 10.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com