Sentence examples for binding profile for a from inspiring English sources

The clinical efficacy of antipsychotic drugs has been associated with a certain binding profile for a set of G protein-coupled receptors (GPCR s.

This information can then be used to infer a binding profile for a query potentially apo protein.

Supplemental Material, Figure 2 (http://www.ehponline.org/docs/2009/0800485/suppl.pdf) shows differential binding profiles for a select group of genes chosen from among the 750 top-ranked genes.

Motivation: The ability to predict binding profiles for an arbitrary protein can significantly improve the areas of drug discovery, lead optimization and protein function prediction.

A binding profile for RNAP (as well as any other protein) can be experimentally determined by measuring position- and species-dependent survival probability along a defined DNA substrate.

This is further supported by the analysis of binding at the Antennapedia (Antp) Hox gene where we find Ubx and Hth binding at multiple peaks across the gene in haltere disc chromatin and also a similar binding profile for Hth in the wing disc (Figure 7).

Further, we used z-scores of the total binding affinity (TBA), which uses a TF binding profile for the whole promoter based on position weight matrices (Molineris et al., 2011).

A comprehensive genome-wide binding profile for Hmt1 was obtained by ChIP-chip using NimbleGen high-resolution tiling microarrays.

10 This was followed in 1993 with the discovery of a second form of the receptor, which shares 44% amino acid identity and a distinct yet similar binding profile for cannabinoid compounds.

Binding distribution histograms built from data collected for either canonical nucleosomes or nucleosomes containing the histone variant H2AZ provided a course-grained profile of the thermodynamically favored intrinsic binding profile for nucleosome deposition.

Isothermal titration calorimetry data showed favorable binding profile for 6aagainst both wild type and MDR769 HIV-1 protease variants.