A recent study demonstrated that AtWRKY TFs bearing the WRKYGQK motif exhibit binding site preferences, which are partly dependent on the adjacent DNA sequences outside of the TTGACY-core motif [ 20].
Higher viral load in sputum samples indicated that there might be factors, including hemagglutinin (HA) binding preference, which favor greater replication in the lower respiratory tract.
But he offered no preference to which is best.
ASR1 showed a binding preference (70%) for gene regions, which is expected for a TF.
Characterization of the glycan-binding specificities of A/shorebird/Delaware/300/2009 (H1N1), one of the shorebird viruses that transmitted efficiently to ferrets, revealed that the airborne-transmitted virus had a strong binding preference for α2,6-linked sialic acids, which is classically found in human influenza viruses.
The topology around the NanB active site suggests that the enzyme would have a preference for α2,3-linked sialoglycoconjugates, which is confirmed by a kinetic analysis of substrate binding.
The wild-type virus showed a mixed binding preference to sialic acids, with α2,3 and α2,6 linkages, which is unusual for an avian virus.
She chose, as her alias, the village of her father's origins, distancing herself from her family, and binding herself to the emanations of that place name, which is pronounced with a regionally southern French preference for a sibilant "S".
Fluorescence titration experiments monitoring the binding of oligopyrimidines to Bs-CspB reveal binding preferences at individual subsites and allow the design of an optimised heptapyrimidine ligand, which is bound with sub-nanomolar affinity.
