Sentence examples for binding preference of a from inspiring English sources
With the assumption that the binding preference of a TF is the same to all its binding sites, we estimated the binding preference of each TF with the following heuristic.
The binding preference of a known transcription factor can be described by the sequences to which it binds.
Third, even if the binding preference of a given transcription factor is known, the task of determining whether it binds to a given promoter is not trivial, mainly due to the high false positive prediction rate [41], [42].
We compiled a dictionary of 1937 motifs, where each motif represented the experimentally-determined binding preference of a human TF or DNA-binding protein.
The use of two distinct influenza receptor glycans enabled us to rapidly determine the binding preference of a virus and thus assess the level of adaptation of the virus hemagglutinin to human host cells.
In short, the binding preference of an αβTCR for a peptide complexed with an MHC molecule dictates which co-receptor subsequently binds, thereby supporting development of that subset lineage.
Refining the human receptor binding preference of an avian influenza virus thus appeared to be necessary for viruses to become airborne.
A common strategy for modeling the binding preferences of a transcriptions factor is to construct a position weight matrix (PWM) from known binding sites.
Therefore, to characterize the binding preferences of a TF, we need to identify many of these potential weak binding sites and to estimate the parameters describing the statistical distribution of those sequences.
Within them, six fragments located at the intronic region of a gene, three fragments located at the downstream region of a gene, but about sixty percent (12 of 21) of fragments located at the upstream region of a gene; this suggested a binding preference of AP-2γ is the upstream region of a gene.
We constructed the binding preference of each TF with a simple heuristic which assesses the binding preference for a TF from a set of known binding sites.
