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Molecular signatures that may contribute to airborne transmission of H5 and H9 influenza virus subtypes are summarized in Table 2. From previous pandemics, we know that only two substitutions in the HA RBD may be required to confer binding preference for receptors on cells of the human URT.
Supplementary Figure 2 GADD45A exhibits binding preference for R-loops.
Significant deviation of read counts between two alleles indicates allelic binding preference for the unique TF.
(b) and (e) Binding preference for PRM toward WW domain and Gd@C82(OH)22.
(a) and (d) Binding preference for WW domain toward PRM and Gd@C82(OH)22.
We constructed the binding preference of each TF with a simple heuristic which assesses the binding preference for a TF from a set of known binding sites.
Future research goals include to develop an (unsupervised) algorithm for predicting the binding preference for TFs without prior knowledge of the known binding sites.
IciA also shows higher binding preference for curved DNA [16].
► Srs2 shows binding preference for ssDNA dsDNA junction.
A DnaK binding preference for L and negative bias for acidic residues is reported (18).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com