Your English writing platform
Discover LudwigExact(4)
We constructed the binding preference of each TF with a simple heuristic which assesses the binding preference for a TF from a set of known binding sites.
These data represent the second experimentally determined putative transcription factor binding preference for a C. parvum protein.
However, true metal specificity requires an exclusive binding preference for a certain metal to an MT peptide due to its innate structural configuration.
The Lsm1-7-Pat1 complex has the binding preference for a U-rich sequence, and an in vitro analysis shows that the complex only binds to U20 but not other 20-mer homo-oligoribonucleotides. To compare the homo-oligomeric RNA-binding ability of Lsm2-3-Pat1C and Lsm1-7-Pat1C, fluorescence anisotropy assay was performed.
Similar(56)
MGB stains, such as DAPI [ 23] and Hoechst [ 24], have a binding preference for A-T rich sequences [ 23, 24].
A position weight matrix (PWM) offers a much more precise description of the binding preferences for a given transcription factor, but the total space of all possible PWMs across each subsequence of a genome cannot be completely explored in an efficient manner.
Interestingly, just a single point mutation (G198N) in Aurora A changes its binding preference for TPX2 into a preference for INCENP and rescues the loss of Aurora B in chromosome alignment and mitotic checkpoint function (Fu et al. 2009; Hans et al. 2009).
Nevertheless, we do not expect a comprehensive database of transcription factor binding preferences for all organisms to be available in the near future.
Lastly, DSL exhibited a strong binding preference for kidney hGGT1 and a modest interaction with liver hGGT1, yet this lectin exhibited no apparent affinity for Pichia pastoris-expressed hGGT1.
Determination of binding preferences for all 8-mers and derivation of associated DNA binding site position weight matrices were calculated using the Universal PBM Analysis Suite and the Seed-and-Wobble motif derivation algorithm [20], [31].
IGFBP-6 is thought to have a binding preference for IGF-II but also binds IGF-I [ 89].
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com